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Being a student of the science of bicycle fit, I'm going to go ahead and interject that even if she tries different saddles but is not properly fit on her bike, there will be uneven pressure on one or more contact points on the bike. If she's got too much pressure on the saddle, then she may not have a good balance on her hands and feet, the other two contact points. When properly fit on the bike, the pressure in those areas balance out and she completely forgets about the bike. The only pain she feels should be her muscles from exertion while riding.
Let me go back to the pressure testing I mentioned earlier... Pressure is important. In addition to just having a cut-out in the saddle, the sit bones (ischial tuberosities) need to be supported properly. If they are not supported properly and a cut-out design is implemented, it can put even higher concentrations of pressure in those soft tissue areas, sometimes causing irreparable nerve damage.
Like Jan mentioned (and I'm trying not to be biased here), Specialized has a saddle fit tool that measures your sit bones and identifies your riding position to determine your correct saddle width. Fizik has started adopting different saddle styles for different positioning on the bike, but they don't take into account the neutral position of the sit bones, and they don't have a wide range of saddles for women. Trek/Bontrager has their new Inform saddles, but it seems to me like they're taking the Specialized BG Technologies and putting a different spin on it to avoid being slapped with a lawsuit. Looks like their saddles are a "domed" shape, which once again, which wouldn't support the rider properly and puts pressure on areas it should not.
Hate to ramble, but I enjoy bike fit related topics.

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